Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Using the concentration-response curve for each cell line, total growth inhibition TGI was defined as the concentration value that produces total growth inhibition and was determined by nonlinear regression analysis using the software Origin 7. The presence adstirngens hydroxyl groups in the structure also enhances the inhibition of lipid peroxidation [ 4041 ].

Published online Aug De La Rosa, and G.

DAI scores significantly increased up between days 6 and 7 in DSS group, as indicated by the incidence of diarrhea, weight loss, and bloody stools. Support Center Support Center. Journal of Pharmacy and Pharmacology. Author information Article notes Copyright and License information Disclaimer.

Amphipterygium adstringens – Useful Tropical Plants

Journal of Crohn’s and Colitis. Journal of Nutritional Biochemistry. Characterisation of complementary and alternative medicine use and its impact on medication adherence in inflammatory bowel disease.

Therefore, the present study aimed to investigate the antioxidant, anti-inflammatory, and immunomodulatory activities of A.

Diseases as caries, periodontitis and gingivitis, oropharyngeal candidiasis, and cancer have had profound effects on human health.

Antioxidant activity and phenolic compounds in selected herbs. Cuachalalate is a legendary plant in Mexico believed to have curative effects. The results suggested the protective potential of AaEE in DSS-induced colitis wdstringens this might be attributed to its phytochemicals compounds that have been found to induce a wide spectrum of activities such as reduction in oxidative stress, suppression of inflammation, modulating numerous signal transduction pathways, and induction of apoptosis.


However, the fact that IL levels did not show significant changes in our experiments is indicative that downmodulation of the inflammatory response by AaEE treatment is not associated with IL levels and perhaps some of the compounds identified in our extracts of A.

Cell lines used in the evaluation of antiproliferative activity. There exists an increasing prevalence of infections worldwide, due to, among adstrinvens reasons, the growing resistance of pathogens to antibiotics and antifungals as well as alterations in the autoimmune system. One of these mechanisms could be related to the well-known antioxidant properties ascribed to the majority of the plant extracts, due to their content in polyphenolic compounds, as it happens with the present extract that contains flavonoids, which has been reported to exert antioxidant properties [ 3839 ].

As mentioned before, oral microbiota diversity is closely related to health adstrinbens and systemic diseases such as cardiovascular and inflammatory diseases and cancer. Medicinal plant-based traditional medicine has long provided ethnopharmacotherapy for the treatment of chronic inflammatory disorders.

The widely employed DSS-induced colitis model recapitulates the histological characteristics of UC [ 89 ].

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are bacteria often isolated from the subgingival biofilm [ 3031 ] and associated with periodontitis and gingivitis. Compared to control mice, DSS mice showed significantly increased histopathological scoring of disease Figure 3 a. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin producing T cell responses.


The Female inflorescence is in raceme about 1.

Evidence-Based Complementary and Alternative Medicine

The Folin-Ciocalteu method [ 22 ] was used to determine the total phenolic content of a 0. However, failures in immune defense or plaque control result in development of gingival inflammation [ 25 — 27 ]. Revista Amphiptterygium de Plantas Medicinais. The scoring system yields minimal and maximal total scores of 0 and 9. The effect of exopolysaccharide-producing probiotic strains on gut oxidative damage in experimental colitis.

The minimum inhibitory concentrations MIC were determined by microdilution broth method according to the Clinical and Laboratory Standards Institute [ 49 ], using well plates. Experimental colitis models have been used to identify therapeutic agents and elucidate the underlying physiologic mechanisms of UC.

Amphipterygium adstringens – Wikipedia

Recent studies have shown that the active component responsible for the plant properties is the anacardic acid [ 19 ] which exerts antioxidant, anti-inflammatory [ 20 ], antitumoral [ 21 ], antiulcer and antimicrobial activities [ 919 ]. Microorganisms in Industry and Environment: The mice were scored daily with respect to body weight, stool formation, and bloody stool.

The colon length was